General Information

Full Name Christopher Ing
Date of Birth 15th February 1986
Languages English


  • 2018
    PhD Biochemistry
    University of Toronto, Toronto, Canada
    • Ion Permeation and Selectivity in Voltage-gated Sodium Channels
      • Studied the molecular structure and function of proteins, specifically voltage-gated sodium channels and other ion channels.
      • Performed all-atom simulations using massive high-performance computing resources and analyzed data using novel methodological approaches.
      • Engaged in multiple national and international collaborations with experimental scientists (electrophysiology, solution and solid-state NMR, x-ray crystallography, cryo-EM), some of which were self-initiated.
      • Supervised multiple undergraduate and graduate level research projects. Presented at the Biophysical Society Conference four consecutive years.
  • 2011
    MSc, Physics
    University of Waterloo, Waterloo, Canada
    • Path-Integral Langevin Dynamics of Complex Molecular Systems: From Low-temperature Quantum Clusters to Biomolecules
      • Studied ultra-low temperature helium clusters using quantum molecular dynamics methods
      • Implemented normal mode path integral molecular dynamics in MMTK, an open-source molecular dynamics software package as part of an international collaboration supported by a Consulat Général de France scholarship (Synchrotron SOLEIL).
  • 2009
    BSc, Computational Physics
    University of Waterloo, Waterloo, Canada


  • 2017 - Present
    Chief Science Officer, Co-founder
    ProteinQure, Toronto
    • Development and application of novel workflows for protein therapeutic design for internal and external programs
  • 2009
    Summer of Code Developer
    • Implemented a real-time smoothed particle hydrodynamics algorithm in a physics education software package using C++/Qt.
  • 2008
    Computational Chemist
    University of Notre Dame, Indiana, United States of America
    • Used a Fortran/Gaussian workflow for performing electronic structure research of hydroxyl water clusters and presented research at the Canadian Undergraduate Physics Conference 2008.
  • 2007
    Medical Imaging Software Developer
    Sunnybrook Health Sciences Centre, Toronto, Canada
    • Worked in the Cardiac Imaging Group contributing to a C++ project for real-time MR imaging by adding multi-slice multi-FOV catheter tracking.
    • Developed on Linux platform with open-source tools such as Eclipse, Bugzilla, CVS, and GDB.
  • 2006 - 2007
    Bioinformatics Researcher
    University Health Network, Toronto, Canada
    • Worked in the Microarray Centre Bioinformatics Group developing a statistical research tool in C# for visualizing gene ontology in expression data sets.
    • Wrote Perl scripts for sequence alignment, annotation of genes, and MySQL database integration.

Open Source Projects

  • 2015-now
    • A beautiful, simple, clean, and responsive Jekyll theme for academics.

Academic Interests

  • Protein Structure and Function
    • Membrane protein structure, dynamics, and function
    • Enzyme dynamics and mechanism of catalysis
    • Protein hydration, flexibility, and loop dynamics
    • Protein and peptide folding
    • Thermodynamics and structure of protein-protein and protein-ligand binding
    • Non-canonical amino acid containing peptides
    • Molecular simulation of proteins (and enhanced sampling)
    • Protein design, grafting, docking, homology modelling, and de novo design
  • Drug Discovery
    • Hit identification and design for binder design
    • Structure-based drug design for lead optimization
    • QSAR and activity prediction and interpretation
  • Ion channels
    • Ion permeation mechanism and selective chemical interactions
    • Channelopathies and other genetic perturbations on channel function
    • Molecular mechanism of channel gating, channel blockers, and pharmacology
  • Scientific Computing
    • Python scripting and software development
    • Novel data visualization and plotting for interpretation of biophysical processes
    • Massively parallel repeated simulations and data analysis workflows
    • Scientific software and workflow development for reproducible research
  • Machine Learning
    • Molecular machine learning of chemical structure
    • Protein structure and dynamics featurization
    • Language models for protein sequence design
    • Structure and property prediction models for protein binder design

Other Interests

  • Hobbies: Cycling, DJing and Turntablism, Film and Television, Cooking and Fine Dining, Mixology and Beer, Science Education.