publications

diverse publications on the topic of protein structure, protein dynamics, computational biophysics, and molecular modelling.

2021

  1. The evolutionary background and functional consequences of the rs2071307 polymorphism in human tropoelastin
    Reichheld, Sean E, Muiznieks, Lisa D, Huynh, Quang, Wang, Nick,  Ing, Christopher, Miao, Ming, Sitarz, Eva E, Pomès, Régis, Sharpe, Simon, and Keeley, Fred W
    Biopolymers 2021

2020

  1. The basic residues in the Orai1 channel inner pore promote opening of the outer hydrophobic gate
    Yamashita, Megumi, Christopher, E, Yeung, Priscilla See-Wai, Maneshi, Mohammad M, Pomès, Régis, and Prakriya, Murali
    Journal of General Physiology 2020
  2. Molecular docking with Gaussian boson sampling
    Banchi, Leonardo, Fingerhuth, Mark, Babej, Tomas,  Ing, Christopher, and Arrazola, Juan Miguel
    Science advances 2020
  3. A sulfur-aromatic gate latch is essential for opening of the Orai1 channel pore
    Yeung, Priscilla SW, Ing, Christopher E, Yamashita, Megumi, Pomès, Régis, and Prakriya, Murali
    Elife 2020

2019

  1. Substrate-based allosteric regulation of a homodimeric enzyme
    Mehrabi, Pedram, Di Pietrantonio, Christopher, Kim, Tae Hun, Sljoka, Adnan, Taverner, Keith,  Ing, Christopher, Kruglyak, Natasha, Pomes, Regis, Pai, Emil F, and Prosser, R Scott
    Journal of the American Chemical Society 2019
  2. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
    Heybrock, Saskia, Kanerva, Kristiina, Meng, Ying, Liang, Anna, Xiong, Zi-Jian, Weng, Xialian, Ah Kim, Young, Collins, Richard, Trimble, William, Pomès, Régis, and others,
    Nature communications 2019
  3. Ion Permeation and Selectivity in Voltage-gated Sodium Channels
    Ing, Christopher
    2019

2018

  1. Mapping the functional anatomy of Orai1 transmembrane domains for CRAC channel gating
    Yeung, Priscilla S-W, Yamashita, Megumi, Ing, Christopher E, Pomès, Régis, Freymann, Douglas M, and Prakriya, Murali
    Proceedings of the National Academy of Sciences 2018
  2. Structural basis for gating pore current in periodic paralysis
    Jiang, Daohua, Gamal El-Din, Tamer M, Lu, Peilong, Pomès, Régis, Zheng, Ning, Catterall, William A, and others,
    Nature 2018
  3. Lipid interactions enhance activation and potentiation of cystic fibrosis transmembrane conductance regulator (CFTR)
    Chin, Stephanie,¬†Ramjeesingh, Mohabir,¬†Hung, Maurita,¬†Ere√Īo-Oreba, June,¬†Ing, Chris,¬†Zeng, Zhi W,¬†Cui, Hong,¬†Pom√®s, R√©gis,¬†Julien, Jean-Philippe,¬†and Bear, Christine E
    BioRxiv 2018
  4. A quantum alternating operator ansatz with hard and soft constraints for lattice protein folding
    Babej, Tomas, Fingerhuth, Mark, and Ing, Christopher
    arXiv preprint arXiv:1810.13411 2018
  5. Coarse-grained lattice protein folding on a quantum annealer
    Babej, Tom√°Ň°,¬† Ing, Christopher,¬†and Fingerhuth, Mark
    arXiv preprint arXiv:1811.00713 2018

2017

  1. The role of dimer asymmetry and protomer dynamics in enzyme catalysis
    Kim, Tae Hun, Mehrabi, Pedram, Ren, Zhong, Sljoka, Adnan,  Ing, Christopher, Bezginov, Alexandr, Ye, Libin, Pomès, Régis, Prosser, R Scott, and Pai, Emil F
    Science 2017
  2. STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate
    Yamashita, Megumi, Yeung, Priscilla S-W, Christopher, E, McNally, Beth A, Pomès, Régis, and Prakriya, Murali
    Nature communications 2017
  3. Structures of closed and open states of a voltage-gated sodium channel
    Lenaeus, Michael J, Gamal El-Din, Tamer M,  Ing, Christopher, Ramanadane, Karthik, Pomès, Régis, Zheng, Ning, and Catterall, William A
    Proceedings of the National Academy of Sciences 2017

2016

  1. Mechanism of amyloidogenesis of a bacterial AAA+ chaperone
    Chan, Sze Wah Samuel, Yau, Jason,  Ing, Christopher, Liu, Kaiyin, Farber, Patrick, Won, Amy, Bhandari, Vaibhav, Kara-Yacoubian, Nareg, Seraphim, Thiago V, Chakrabarti, Nilmadhab, and others,
    Structure 2016
  2. Simulation studies of ion permeation and selectivity in voltage-gated sodium channels
    Ing, C, and Pomes, R
    Current Topics in Membranes 2016
  3. Structure and dynamics of extracellular loops in human Aquaporin-1 from solid-state NMR and molecular dynamics
    Wang, Shenlin,  Ing, Christopher, Emami, Sanaz, Jiang, Yunjiang, Liang, Hongjun, Pomès, Régis, Brown, Leonid S, and Ladizhansky, Vladimir
    The Journal of Physical Chemistry B 2016
  4. Predicting protein thermostability upon mutation using molecular dynamics timeseries data
    Fleming, Noah, Kinsella, Benjamin, and Ing, Christopher
    bioRxiv 2016

2015

  1. The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD
    Calmettes, Charles, Buckwalter, Carolyn M, El Bakkouri, Majida, Chieh-Lin Lai, Christine, Pogoutse, Anastassia, Gray-Owen, Scott D, Pomès, Régis, Moraes, Trevor F, and others,
    Nature communications 2015

2014

  1. Inclusion of trial functions in the Langevin equation path integral ground state method: Application to parahydrogen clusters and their isotopologues
    Schmidt, Matthew, Constable, Steve,  Ing, Christopher, and Roy, Pierre-Nicholas
    The Journal of Chemical Physics 2014
  2. Modification and periplasmic translocation of the biofilm exopolysaccharide poly-ő≤-1, 6-N-acetyl-d-glucosamine
    Little, Dustin J, Li, Grace,  Ing, Christopher, DiFrancesco, Benjamin R, Bamford, Natalie C, Robinson, Howard, Nitz, Mark, Pomès, Régis, and Howell, P Lynne
    Proceedings of the National Academy of Sciences 2014
  3. Catalysis and Selectivity of Na+ Permeation in Bacterial Sodium Channel NaVAb
    Ing, Christopher, Chakrabarti, Nilmadhab, Payandeh, Jian, Zheng, Ning, Catterall, William A, and Pomès, Régis
    Biophysical Journal 2014

2013

  1. Langevin equation path integral ground state
    Constable, Steve, Schmidt, Matthew,  Ing, Christopher, Zeng, Tao, and Roy, Pierre-Nicholas
    The Journal of Physical Chemistry A 2013
  2. Catalysis of Na+ permeation in the bacterial sodium channel NaVAb
    Chakrabarti, Nilmadhab,  Ing, Christopher, Payandeh, Jian, Zheng, Ning, Catterall, William A, and Pomès, Régis
    Proceedings of the National Academy of Sciences 2013

2012

  1. A path-integral Langevin equation treatment of low-temperature doped helium clusters
    Ing, Christopher, Hinsen, Konrad, Yang, Jing, Zeng, Toby, Li, Hui, and Roy, Pierre-Nicholas
    The Journal of Chemical Physics 2012